akt1 inhibitor api 1 (Tocris)
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akt1 inhibitor api 1
Akt1 Inhibitor Api 1, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 17 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/api+1/API-1/pm39332480-66-47-52
Average 92 stars, based on 17 article reviews
Akt1 Inhibitor Api 1, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 17 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/api+1/API-1/pm39332480-66-47-52
Average 92 stars, based on 17 article reviews
akt1 inhibitor api 1 - by Bioz Stars,
2026-09
92/100 stars
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other:Article Title: Malignant ascites determine the transmesothelial invasion of ovarian cancer cells. Article Snippet: The exact role of malignant ascites in the development of intraperitoneal ovarian cancer metastases remains unclear.. In this report we sought to establish if ascites can determine the efficiency of transmesothelial invasion of ovarian cancer cells, and, if so, whether the fluid generated by highly aggressive serous and undifferentiated tumors will promote the invasion more effectively than ascites from less aggressive clear cell and endometrioid cancers.. The study showed that the invasion of ovarian cancer cells (SKOV-3 and primary cancer cells) across monolayered peritoneal mesothelial cells was elevated upon mesothelial cell exposure to fluid produced by serous and undifferentiated cancers, as compared with cells subjected to ascites from clear cell and endometrioid tumors. Article Title: Oxidative stress contributes to hepatocyte growth factor-dependent pro-senescence activity of ovarian cancer cells. Article Snippet: Cite this article as: Justyna Mikuła-Pietrasik, Paweł Uruski, Martyna Pakuła, Konstantin Maksin, Sebastian Szubert, Aldona Woźniak, Eryk Naumowicz, Dariusz Szpurek, Andrzej Tykarski and Krzysztof Książek, Oxidative stress contributes to hepatocyte growth factor-dependent pro-senescence activity of ovarian cancer cells, Free Radical Biology and Medicine, http://dx.doi.org/10.1016/j.freeradbiomed.2017.06.015 Article Title: An early glycolysis burst in microglia regulates mitochondrial dysfunction in oligodendrocytes under neuroinflammation Article Snippet: Article Title: Mechanisms of carboplatin- and paclitaxel-dependent induction of premature senescence and pro-cancerogenic conversion of normal peritoneal mesothelium and fibroblasts. Article Snippet: Carboplatin (CPT) and paclitaxel (PCT) are the optimal non-surgical treatment of epithelial ovarian cancer (EOC).. Although their growth-restricting influence on EOC cells is well known, their impact on normal peritoneal cells, including mesothelium (PMCs) and fibroblasts (PFBs), is poorly understood.. Here, we investigated whether, and if so, by what mechanism, CPT and PCT induce senescence of omental PMCs and PFBs. Article Title: The peroxidase PRDX1 inhibits the activated phenotype in mammary fibroblasts through regulating c-Jun N-terminal kinases Article Snippet: Before the individual experiments, cells were starved for 48 h in 0.25% FBS DMEM and pretreated for 1–2 h with 25 μM JNK inhibitor, SP600125 (Tocris Bioscience), 2 μM JNK-IN-8 (a kind gift from Dr. Nathanial Grey, DFCI, Boston) or 10 μM Article Title: PI3K/Akt signaling pathway triggers P2X7 receptor expression as a pro-survival factor of neuroblastoma cells under limiting growth conditions. Article Snippet: LY294002, API-1, KN93, H89, A740003, and Control:Article Title: The Role of Akt/Rab5A Signalling in Regulating Cell Migration of MDA-MB-231 Breast Cancer Cell Line Article Snippet: .. Akt and Rab5A Inhibitors Dynasore (20 mM) (Selleckchem, S8047), as well as Pitstop 2 (25 mM) (Abcam, ab120687), were employed to suppress dynamin, clathrin-mediated endocytosis, API-1 (5 μM) to inhibit Article Title: The Role of Akt/Rab5A Signalling in Regulating Cell Migration of MDA-MB-231 Breast Cancer Cell Line Article Snippet: To test cells for mycoplasma, an EZ-PCR Mycoplasma Based detection (Geneflow, K1-0210, UK) was utilized on a routine basis. .. Dynasore (20 mM) (Selleckchem, S8047), as well as Pitstop 2 (25 mM) (Abcam, ab120687), were employed to suppress dynamin, clathrin-mediated endocytosis, API-1 (5 μM) to inhibit |